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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
37.58
Human Site:
S858
Identified Species:
63.59
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S858
N
I
K
S
L
V
V
S
Q
F
T
T
F
L
S
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S858
N
I
K
S
L
V
V
S
Q
F
T
T
F
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
S955
N
I
K
S
L
V
V
S
Q
F
T
T
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
S852
N
I
K
S
L
V
V
S
Q
F
T
T
F
L
S
Rat
Rattus norvegicus
NP_001099948
974
110023
S823
N
I
K
S
L
V
V
S
Q
F
T
T
F
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
Q762
R
L
D
G
S
M
P
Q
K
K
R
V
E
S
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
S848
T
I
K
S
I
V
V
S
Q
F
T
S
F
L
S
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
S793
T
V
K
S
M
V
V
S
Q
F
T
G
F
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
S915
D
D
K
A
I
V
V
S
Q
W
T
S
V
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
S937
T
T
K
S
I
V
V
S
Q
F
T
S
F
L
D
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
M677
I
L
R
L
D
G
S
M
N
A
K
K
R
A
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
M759
I
L
R
L
D
G
A
M
T
V
K
K
R
T
Q
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
Q668
G
F
Q
T
V
K
L
Q
G
S
M
S
P
T
Q
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
S1075
K
M
K
S
L
V
I
S
Q
F
T
S
F
L
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
N.A.
80
66.6
N.A.
46.6
N.A.
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
N.A.
93.3
80
N.A.
80
N.A.
N.A.
80
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
0
0
73.3
P-Site Similarity:
13.3
N.A.
N.A.
13.3
33.3
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
15
0
0
0
0
0
0
0
0
0
22
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
65
0
0
65
0
0
% F
% Gly:
8
0
0
8
0
15
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
43
0
0
22
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
72
0
0
8
0
0
8
8
15
15
0
0
0
% K
% Leu:
0
22
0
15
43
0
8
0
0
0
0
0
0
72
0
% L
% Met:
0
8
0
0
8
8
0
15
0
0
8
0
0
0
0
% M
% Asn:
36
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
15
72
0
0
0
0
0
22
% Q
% Arg:
8
0
15
0
0
0
0
0
0
0
8
0
15
0
0
% R
% Ser:
0
0
0
65
8
0
8
72
0
8
0
36
0
8
50
% S
% Thr:
22
8
0
8
0
0
0
0
8
0
72
36
0
15
0
% T
% Val:
0
8
0
0
8
72
65
0
0
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _